Human primary cells for

in-vitro experiments that

mirror in-vivo like

performance

At the Amnion Foundation we are advancing science by providing high-quality, donor-matched, primary cells. Our expertise in primary cell isolation provides researchers with high-quality resources, including expertise in multi-system primary cell culture, cGMP biobanking, and quality control testing services to support discoveries that can transform human health today.

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Realizing the Full Potential of Every Donated Tissue

The Amnion Foundation, founded by scientists to fill a niche, is a 501(c)3 non-profit organization dedicated to supporting the development and advancement of technologies that utilize one or more cellular components of donated tissues.  Our expertise in primary cell isolation helps researchers access reliable primary cells for advancing maternal-fetal health, regenerative medicine, toxicology, and NAMs development. Our proprietary isolation and culturing techniques ensure that your experiments are powered with primary cells that retain in-vivo like functions during in-vitro culture. We offer donor-matched lots of healthy and disease-state primary cells to meet your experimental needs. 

woman working in laborator

Advancing NAMs Research & Development

We offer primary cells from several different organ systems to accelerate development of New Approach Methodologies (NAMs) to advance your NAMs reproducibility and ensure repeatable, measurable metrics. We offer primary cell, donor matched lots from Lung/Pulmonary Model Systems, Placental/Decidual/Birth Tissue Model Systems; and coming soon: Kidney/Renal Model Systems.

 At the Amnion Foundation, we support scientists who push the boundaries of discovery. Explore our website to learn about our products & services, connect through our seed grant program, meet the team driving innovation, and visit our shop to support ongoing research.

Together, we turn research into real-world impact.

 

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cGMP Biobanking & Biorepository Services –

Ensuring the Future of your Experiments

Our advanced biobanking services protect essential tissue and cellular resources for future scientific use. 

Every preserved sample ensures the reproducibility, success, and relevance of future of your experimental models and NAMs. We help researchers and scientists in the fields of regenerative medicine, maternal-fetal health, and disease modeling by combining superior culture techniques and preservation.

We also offer biobanking and biorepository services to companies in the early stages of discovery and translation. Whether you need extra freezer space or need to establish an offsite backup inventory – we have a solution that will meet your needs.  

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Questions & Answers

How does the Amnion Foundation support birth tissue research with primary cells?

Amnion Foundation specializes in isolating and culturing donor-matched primary cells from birth-associated tissues, including Hofbauer cells and cytotrophoblasts (CTBPRO2™). Our proprietary techniques ensure these cells retain in-vivo-like functions for accurate in-vitro research, serving the scientific community.

What makes Amnion Foundation a key player in primary-cell isolation?

Amnion Foundation excels in primary cells by providing donor-matched lots of healthy and disease-state primary cells from several different organ systems – birth tissue, pulmonary, renal, and skin. Our rigorous isolation and culturing methods ensure high-quality, functional cells for advanced research and NAMs. 

Where can I find a reliable resource for primary cells?

Amnion Foundation is dedicated to advancing research with high-quality primary cells from birth-associated tissues. We offer a range of products, including HUVEC, Hofbauer, and Cytotrophoblast cells, ensuring researchers have access to physiologically relevant biological materials.

What types of birth-tissue cells does Amnion Foundation offer for research?

Amnion Foundation provides donor-matched, placental primary cells:  Cytotrophoblasts (CTBPRO2™), Microvascular Endothelial Cells (MVECPRO2™), Placental Macrophages – Hofbauer cells, Placental Stem Cells (PSCPRO2™),  and placental stromal cells – all isolated from chorionic villus tissue. These cells are crucial for studies on  placental invasion, vertical transmission, angiogenesis, barrier models, and NAMs, ensuring researchers across the globe have access to physiologically relevant primary cells.

Does Amnion Foundation offer cytotrophoblast culture products?

Amnion Foundation provides high-quality human Cytotrophoblasts (CTBPRO2®) that are isolated and propagated from full-term placenta. These lineage-restricted progenitor cells are immuno-positive for CD49f and express key trophoblast markers, offering a non-controversial resource for researchers studying placental biology. Amnion Foundation offers primary human cytotrophoblasts (CTBPRO2™) and a proprietary, specialized media –  CTBPRO2GRO™ – for their culture. These germinal-origin epithelial cells are essential for studying the maternal-fetal barrier, trophoblast differentiation, and placental development. 

Can Amnion Foundation assist with Cytotrophoblast Isolation for research?

Amnion Foundation provides high-quality human Cytotrophoblasts (CTBPRO2®) that are isolated and propagated from full-term placenta. These lineage-restricted progenitor cells are immuno-positive for CD49f and express key trophoblast markers, offering a non-controversial resource for researchers studying placental biology.

What are Hofbauer Cells and their role in placental studies?

Hofbauer Cells are specialized tissue macrophages found in the placenta’s chorionic villi. Amnion Foundation provides these fetal-origin cells, which are vital for understanding inflammation and infectious diseases within the placenta. Our Hofbauer cells are enriched based on surface protein expression and cryopreserved immediately after isolation.

How does Amnion Foundation ensure the quality of its endothelial cells?

Amnion Foundation ensures the quality of its endothelial cells, including HUVECPRO2® and MVECPRO2®, through rigorous Quality Control processes. These cells are characterized by surface markers like CD31, CD29, and VE-cadherin, and confirmed for tube formation competency, providing reliable tools for endothelial cell biology. 

What services does Amnion Foundation provide for stem cell biology and regenerative medicine?

Amnion Foundation supports stem cell biotechnology by offering primary cells from birth tissues, including placental mesenchymal stromal cells. Our focus is on providing cells that maintain in-vivo-like functions during in-vitro culture, advancing research in regenerative medicine and developmental biology. 

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